Common 5 amino 1mq side effects are typically mild and transient, occurring primarily during the first 1-2 weeks of treatment
Investigators are particularly interested in determining the mechanisms by which effects observed in murine models relate to broader mammalian metabolic regulation, and whether different experimental conditions (young vs aged models, healthy vs metabolically compromised states) show differential responses to NNMT inhibition
Unlike full HGH, it does not raise IGF-1, does not affect blood sugar, does not stimulate growth in non-fat tissue, and does not interfere with the pituitary's own growth hormone signalling
But it also raises IGF-1, disrupts glucose metabolism, and can accelerate unwanted tissue growth
NNMT as a metabolic enzyme, controls how cancer cells use energy and nutrients
You still need a caloric deficit