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The second metabolite, acrolein, is produced when 4-hydroxy cyclophosphamide is activated to form active phosphoramide

FIGURE 1 Next, to determine the neurotoxic effect of peroxynitrite on cultured SGNs, the cultured SGNs were treated with different concentrations (100 or 200 M) of peroxynitrite for 24 or 48 h, respectively (Figure 2A)

The 0.9% concentration used in pharmacopoeia-grade bacteriostatic water is the standard specification verified for compatibility with most reconstitution applications

Targeting of Th1-associated chemokine receptors CXCR3 and CCR5 as therapeutic strategy for inflammatory diseases