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Additionally, medical conditions like diabetes and neurodegenerative diseases can impair normal NAD+ metabolism, further depleting reserves

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Biochemical assay kits for alanine aminotransferase (ALT), aspartate aminotransferase (AST), total cholesterol (TC), triglyceride (TG), and superoxide dismutase (SOD) were purchased from Nanjing Jiancheng Bioengineering Institute (Nanjing, China)

at least one study suggests that this constant is also applicable for MD patients