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SASP is characterized by the release of inflammatory and tissue-degrading molecules that can impair tissue function and structure, potentially leading to age-related deterioration

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Moreover, at low concentration, -Glu-Glu potentiated the responses of glutamate on NMDA receptors

Drug-induced liver injury (DILI) is the leading cause of acute liver failure in the U.S

mGluRs have eight different subtypes, some of which can be coupled to adenylate cyclase and phospholipase C

PMID 17052662