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However, lifestyle interventions are notoriously difficult to maintain [135], suggesting that some patients may benefit from pharmacological therapy

Moody, W

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Because of ubiquitination and subsequent proteolysis, Nrf2 turns over rapidly with a half-life of 715 min, which increases to 30100 min in the presence of oxidative or electrophilic stress (McMahon et al

The toxicity can be explained by the tendency of these molecules to bind or destroy important biomolecules

Treat immune-boost language as a hypothesis, not a demonstrated outcome