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Therefore, it was conservatively hypothesized that the administration of 300 mg/d or other doses of GSH warrants further investigation in future studies

Maxfield FR, van Meer G

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So even the topical route, which is the evidence-backed one, should be described as supported by small, sometimes industry-affiliated human cosmetic studies with modest effect sizes, not as proven. The correct posture toward topical GHK-Cu is cautious optimism grounded in real but imperfect human data which is still a materially stronger position than the injectable route can claim

The choice between them in a research context depends entirely on the experimental question: single-pathway isolation vs