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The molecular dynamics simulations were performed with a 100 ns NPT ensemble employing GAFF2 forcefield in the temperature of 310 K, integration time step of 2 fs, and non-bond cutoff distance of 6.0

10.1074/jbc.M116.752618 56 HassonS

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Studies as early as 1998 validate the use of correct oral treatment as being equally effective as injections, with a conclusion that stated: In cobalamin deficiency, 2,000mcg of cyanocobalamin administered orally on a daily basis was as effective and may be superior for raising blood B12 levels as 1,000mcg administered intramuscularly on a monthly basis

Current Pharmaceutical Design, 2014, 20(7):1121-1125 2.Sikiric P, Seiwerth S, Brcic L, Sever M, Klicek R, Radic B, Drmic D, Ilic S, Kolenc D

Mesenchymal stem cells derived from hPSC via neural crest attenuate chemotherapy-induced premature ovarian insufficiency by ameliorating apoptosis and oxidative stress in granulosa cells