The study sponsor had no role in the study design
These injections are intramuscular shots that deliver a high dose of vitamin B12 directly into the bloodstream, ensuring rapid absorption
1 2 "Blind loop syndrome: MedlinePlus Medical Encyclopedia"
Because it is an injection, it should always be given by a trained provider, and we start every patient with a consultation and testing to confirm the treatment is right for them
They are usually safe, but some people might have reactions
It was initially planned to recruit 20 analyzable patients (who completed the two-treatment periods) to have 80% power to detect, with a two-sided test at 0.05 significance level, an absolute decrease in percentage over total target of 10% under the A-dopamine period compared with the control (oral l-dopa-alone treatment) period, by assuming a standard deviation of 15% and a within-patient correlation of 0.5 to account for the crossover design