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Mutations in Parkin or PINK1 impair these proteins, leading to the accumulation of damaged mitochondria, reduced energy production, and elevated levels of reactive oxygen species (ROS) 39

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Therefore, caution should be taken when extrapolating findings from this work to individuals who were infected after completing their vaccination or were infected with more recent SARS-CoV-2 variants

In Warren MJ, Smith (eds.)

Given the central role of ALOX12/15 in MDSC biology, targeting this enzyme offers significant therapeutic potential