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Rapid acetylators were competent in isoniazid acetylation but the drug was cleared less efficiently in the slow acetylator group, which resulted in elevated serum concentration and led to adverse neurologic side effects due to an accumulation of unmetabolized drug (Brockton et al., 2000)

Brain Untargeted Metabolomics Metabolomic studies on brain tissue and CSF are somewhat lacking with, for instance, no studies thus far on CSF in patients with autism

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