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E-cigarette companies have been accused of deliberately targeting young adults and adolescents via tactics such as leveraging social media, sponsorship of festivals and music events, and introduction of flavors that appeal to youth

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In 1929, Lucky Strikes slogan Reach for a Lucky instead of a Sweet openly promoted cigarettes as a way for women to keep slim

Available at: fda.gov/ TobaccoProducts/Labeling/ProductsIngredientsComponents/ucm456610.htm

The medial habenula is enriched in 5*, 3*, 4* nAChRs, which have been shown to mediate nicotine aversion, drug-taking behavior, and/or withdrawal (96101)