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Human age-related cataracts: Epigenetic suppression of the nuclear factor erythroid 2-related factor 2-mediated antioxidant system

References: Office of Dietary Supplements, National Institutes of Health

Unique regulation of enterocyte brush border membrane na-glutamine and na-alanine co-transport by peroxynitrite during chronic intestinal inflammation

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The observation in this study in hepatocytes that protein-SSG formation by either GSSG accumulation or treatment with a direct S -glutathionylation induction agent resulted in IKK--SSG formation, leading to its suppression, was supported by a previous study reporting that S -glutathionylation was associated with suppressed IKK- activity in epithelial cells 41