Patients who are also optimizing hormonal status should be aware that sex hormones interact with MOTS-c signaling
However, BPC-157 has never completed human clinical trials, so its safety profile in humans is unknown
23 Supplementation of 1 mg daily is recommended for patients with specific risk factors (e.g., bariatric/gastric surgery patients, those with severe malnutrition, chronic alcohol use, chronic hemolytic anemia and conditions with high cell turnover, and use of antimetabolite medications such as methotrexate)
Grip strength as a simple yet powerful predictor of all-cause mortality [16:45]
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not on the tirzepatide label, incidence unknown: Ahern Cureus 2025