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Am J Hypertens 1998

Reports of adverse effects are rare and typically mild when they occurmost commonly including temporary headache, dizziness, or slight nausea, usually associated with dosing adjustments

MOTS-c translocates to the nucleus during metabolic stress to regulate antioxidant and glucose metabolism genes via AMPK activation [4]

Gastrointestinal Studies: Investigated for its ability to influence mucosal integrity, gastric ulcer models, and intestinal protection