The conditions that have been associated with glutathione deficiency include the following: Neurodegenerative diseases such as Alzheimers, Parkinsons and Huntingtons disease and ALS Pulmonary diseases such as COPD, asthma, and acute respiratory distress syndrome Immune system disorders Cardiovascular diseases such as high blood pressure, elevated cholesterol, and heart attacks Chronic age-related disorders such as cataracts, macular degeneration, hearing impairment, and glaucoma Liver disease Cystic fibrosis Aging processes (Pizzorno, 2014)
Glutathione Metabolism and its Implications for Health
PubMed, doi:10.1016/j.tjog.2013.04.016
This study investigated whether GSH deficiency induces epigenetic alterations that impair Vitamin D (VD) metabolism genes in the livers of HFD-fed mice
In the context of transcriptomic analyses, it is generally observed that GST expression is downregulated in susceptible interactions (Sun et al., 2016
Brain angiotensin and anxiety-related behavior: The transgenic rat TGR(ASrAOGEN)680