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Comparative epidemiology of tobacco-related cancers

Reduced blood flow from nicotine Nicotine causes vasoconstriction, which narrows the small vessels that supply your lips

Sitkauskiene, B., and P

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Several pulmonary studies enrolled cannabis-only groups and demonstrate large-airway dysfunction and symptomatology independent of tobacco (9,11), while population cohorts show non-linear lung-function patterns with cannabis exposure after tobacco adjustment (13) and increased odds of airflow obstruction at very high lifetime use (64)