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Modern GLP-1 receptor agonists and dual agonists have attracted enormous attention for metabolic and weight management applications

The peptide contains an internal disulfide bond between the two cysteine residues, which is critical for its three-dimensional conformation

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Toxins 12 (9), 558

EHMT2/G9a stood out as a potential target: it is an epigenetic regulator expressed in immune cells, including macrophages, and its previously determined half maximal effective concentration (EC 50 ) (PubChem AID: 504332) matches the effect range (10100 M) seen in our study 39