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P.LiJ.et al (2019)

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Ferroptosis is an iron-dependent lipid peroxidation and ROS-induced programmed cell death (PCD) modality that relies on iron-mediated oxidative damage, increased iron accumulation, and free radical production, and a fatty acid supply with increased lipid peroxidation is critical for the induction of ferroptosis 22

In the current era of single-cell analysis, a computational model for studying metabolic phenotypes in the tumor microenvironment at a single cell level has also been developed (100), along with methods for imaging single-cell behavior in various microenvironments (101)

doi: 10.1021/bi00353a016 Vandenberg, JI, King, GF and Kuchel, PW (1985)

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