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doi: 10.1016/S0140-6736(20)32511-3 Summary Keywords chronic liver disorder, metabolic syndrome, non-alcoholic fatty liver disease, oxidative stress, oral glutathione Citation Santacroce G, Gentile A, Soriano S, Novelli A, Lenti MV and Di Sabatino A (2023) Glutathione: Pharmacological aspects and implications for clinical use in non-alcoholic fatty liver disease
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Figure 2: The synthesis of GSH Hopkins first discovered glutathione as early as 1921 , than divided it into reduced glutathione (GSH) and oxidative type (GSSG) two kinds.GSH exists in all living cells, its higher in yeast, wheat germ and liver, 100~1000 mg/100 g.According to recent data, S.c erevisiae Jacqueline Nottingham-5-8 strains of GSH content of up to 3058 mg/3058 g.In dry yeast type oxidation GSH exists, and almost all people in red blood cells were reduced glutathione, GSH can be synthesized in the red blood cells.Glutathione molecule contains a lively mercapto-SH, susceptible to oxidative dehydrogenation, two molecules of reduced glutathione (GSH) into a molecular dehydrogenation oxidation type glutathione (GSSG).Peptide by oxidation type in two three disulfide bond together, which play an important physiological role in living organisms is reduced glutathione, GSSG as GSH is physiological activity
