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Two periods of 90 days of trimetazidine (60 mg/day) also increased cardiac phosphocreatine/ATP ratio in nine patients (but three patients showed a decrease), which indicated improved mitochondrial energetics [146]

Check out the preprint on BioRxiv

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doi: 10.1371/journal.pone.0005515

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Meudt O., Klinikum Memmingen, Department of Neurology