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In exploratory random-effects (REML) meta-regression based on the primary pooled dataset, neither treatment duration nor ALC daily dose showed a clear association with the standardized treatment effect

This study involved a novel use of dihydrotestosterone (DHT) as an indicator of oxidative stress and wound healing (HGF and HPF cells exhibit high expression of the androgen receptor)

In particular, hypoxia was unique to CD8 + T cells and the G2-M checkpoint was shared by CD4 + T and plasma cells in the Hallmark gene set ( Figure 8I )

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106,127,128 Intriguingly, both enzymatic and non-enzymatic antioxidant system components exhibit their effects in coordination with each other to contribute to redox homeostasis and cell fate using NADPH as the ultimate donor of reductive power