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In 1987 he and Bernhard Kreymann launched a study with other colleagues to investigate the physiological effect of another synthesised fragment of human GLP-1 directly in humans

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In August 2024, the FDA banned compounding pharmacies from producing both peptides, citing cardiovascular safety concerns such as tachycardia and arrhythmias, along with a lack of robust human trial data

the analog is: hexanoic-tyrosine-isoleucine-(6)-amino-hexanoic amide

This is why pre-mixed blends require specific dosing intervals rather than continuous administration

Philippot G, Forsberg E, Tahan C, Viberg H, Fredrickson R