PMID: 29155147): 5-Amino-1MQ showed NNMT selectivity with IC50 of 1.2 microM Reduced body weight and white adipose mass in diet-induced obese mice over 11 days No effect on food intake, suggesting metabolic rather than appetitive mechanism Nicotinamide N-methyltransferase inhibition mimics and boosts exercise-mediated improvements in muscle function in aged mice , published in Scientific Reports (Dimet-Wiley AL et al., 2024
When deficiency develops, symptoms can include fatigue, weakness, numbness or tingling in the feet or hands, difficulty walking, mood changes such as depression, and problems with memory or concentration. Untreated, severe deficiency can lead to anemia and neurological damage, so medical attention and proper supplementation are essential. Why Choose B12 Injections
References Markle HV, Greenway DC
DNA Production: B12 is vital for making DNA, which is needed for cell growth and division
How Often Should You Get a B12 Shot
What are your wellness goals