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Dietary adjustments, probiotics and prebiotics use, and fecal microbiota transplantation might exert therapeutic effects on OA by inhibiting cartilage catabolism or apoptosis [144,145,146,147]

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Another potent antioxidant, resveratrol, is a naturally occurring polyphenol found in grapes, berries, and red wine [216,217,218]

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Additionally, current research aims to ameliorate several aspects of the inflammatory cascade