Thus, scientists must note that unanticipated reactions may emerge as research progresses
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Bosentan (BOS), an unselective endothelin receptor blocker, increased desmin + hepatic stellate cells (HSCs) numbers and VEGF release of HSCs in rat (Bahde et al., 2013), potentially aiding cell entry via increasing hepatic sinusoid permeability
Potential Side Effects As with any injection therapy, some patients may experience minor injection-site reactions including redness, mild pain, itching, or swelling
Dysregulation in any of these regulatory nodes may induce ultrastructural mitochondrial abnormalities and functional impairments, ultimately precipitating axonal degeneration and neuronal apoptosispathological hallmarks that define neurodegenerative pathogenesis (Hong et al., 2024)
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