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Oxidative stress was evidenced by reduced activity of the antioxidant enzymes glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD), along with increased MDA levels

The ADA Standards of Care 2024 acknowledge oxidative stress as a mechanistic contributor to diabetic complications but stop short of recommending specific antioxidant supplementation due to inconsistent clinical outcomes data

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Due to this effectiveness, many dermatology clinics offer injections for skin whitening, anti-aging treatments, and detox therapy

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