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Hydroxocobalamin is the form the NHS uses because it lingers in the body longer than cyanocobalamin, and its pharmacology supports dosing intervals of up to three months once levels are stable

(2017) Guideline for Primary Care: Investigation and management of B12/folate deficiency

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Other Studies Joint repair effect: In the rabbit collagenase-induced knee osteoarthritis model, AOD 9604 can promote cartilage regeneration, and the effect is better when combined with hyaluronic acid injection

Some researchers find this approach reduces waste, though it requires more careful handling and is not universally recommended