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Toll-like receptor 4 deficiency reduces oxidative stress and macrophage mediated inflammation in hypertensive kidney

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The dimer interface is formed by the interaction between loop 2 of one monomer and loop 1 of the other, stabilized by hydrogen bonds and salt bridges, resulting in a more open and flexible active site pocket compared to other GCTs

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Therefore, Trx may have a neuroprotective function in individuals suffering from acute ischemic stroke, and serum Trx levels are novel diagnostic and prognostic indicators that are also closely related to the severity of intracranial hemorrhage and long-term mortality

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