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In breast cancer, GPx2 is commonly overexpressed in the mammary carcinomas of mouse models of breast cancer induced by carcinogens, which is consistent with its up-regulation in human breast cancer [19]

Dox is a highly cardiotoxic drug, whereas its damaging spectrum affects most of the organs by multiple pathogenic cascades

mitochondrial proteomic analysis

Acknowledgements We sincerely thank Ya-Hui Tsai, PhD, research specialist in the Division of Pediatric Surgery, Department of Surgery, Far-Eastern Memorial Hospital for editing the figures in the manuscript

doi: 10.1016/j.freeradbiomed.2011.10.486 83 JainALamarkTSjttemELarsenKBAwuhJAvervatnAet al

But that requires a $208 up-front investment and comes with a considerably weaker formula