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A 25 to 27 gauge needle is appropriate, as it minimizes discomfort and is sufficient for penetrating the subcutaneous layer without reaching the muscle

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Conflict of interest JDC has received grants and personal fees from AstraZeneca, Boehringer-Ingelheim, GSK, Zambon, and Insmed Incorporated, a grant from Gilead, and personal fees from Novartis and Chiesi

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