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Infliximab-loaded hydrogels alleviate joint inflammation with minimal systemic exposure (49)

Common cycles are 8 to 12 weeks on, then 4 to 8 weeks off, but protocols differ by peptide and clinical response

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J Physiol Pharmacol 66(4):581590 Klicek R, Sever M, Radic B, Drmic D, Kocman I, Zoricic I et al (2008) Pentadecapeptide BPC 157, in clinical trials as a therapy for inflammatory bowel disease (PL14736), is effective in the healing of colocutaneous fistulas in rats: role of the nitric oxide-system

Matrix metalloproteinases (MMPs) interrupt the proper working of these glycoproteins, leading to the dysfunction of BBB [6]