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Further mechanistic studies have found that treatment with TMZ promoted cardiac Nrf2 expression, indicating that TMZ enhanced the clearance of oxidative stress by activating the GSH system through the Nrf2 signaling pathway [210]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Weerarathne P., Reichard M., Miller C., Scimeca R.C

Peptides requiring excessive agitation, extended dissolution times, or failing to fully dissolve have likely degraded

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