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The emerging characterization of separate dopamine- and GABA (-aminobutyric acid)-dependent neural systems within the ventral tegmental area (VTA), which can mediate the acute aversive and rewarding psychological effects of nicotine, is providing new insights into how functional interactions between these systems might determine vulnerability to nicotine use
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Variables with missing rates exceeding 10% were addressed using multiple imputation
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Infants born to women who smoked and drank beyond the first trimester of pregnancy had a SIDS risk 11.79 times greater (98.3% CI, 2.59-53.70) than infants who were not exposed to either substance after the first trimester of pregnancy
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