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however, two additional legumes (broad bean and lupine) appear to lack this glutathione analog in all assayed tissue types (Matamoros et al., For biosynthesis of glutathione and homoglutathione share a common first reaction, i.e., the synthesis of -glutamylcysteine, but the chemical diversity results from altered specificity for the nucleophilic amino acid in the second reaction of the pathway

However, chronic stress, whether it is from toxins, poor diet, sleep deprivation, smoking, excess sugar, or other stressors, eventually exhausts glutathione levels

Is its dysfunction a pathological trigger or a consequence of the disease

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