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The animal data suggests these effects can produce measurable weight loss without requiring reduced food intake

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If folate deficiency is suspected, it is reasonable to give oral folic acid (0.4 1 mg/day) without doing laboratory investigation for deficiency at least until the hemoglobin and mean corpuscular volume normalizes (or longer if the underlying cause cannot be eliminated)

Stress and long work hours made recovery challenging

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Hydroxocobalamin has a long safety record, no meaningful overdose risk because excess is excreted in urine, and a very low rate of allergic reactions