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This study comprehensively establishes the causes and outcomes of acute chest syndrome

Further, GSH transferase which is involved in drug detoxification through conjugation of xenobiotics with GSH exhibits polymorphic forms which affect its detoxification efficacy

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Inflamed synovium produces prostaglandins, leukotrienes, ROS, cytokines, chemokines, and adipokines, all of which contribute to cartilage breakdown and further exacerbate inflammation (Scanzello and Goldring, 2012)