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Randomized trials with Se as part of multivitamin supplementation in Se-deplete areas were shown to reduce gastric cancer, stroke and overall mortality, but did not reduce the risk for hypertension, CVD or cataracts ( Reference Huang, Caballero and Chang 9 )

Horowitz, M.A

187,500,505,506 The increased activity and expression of CD38 following aging is responsible for the age-associated decrease in NAD + level and defective mitochondrial function, which is at least partially regulated by the NAD + /SIRT3 signaling pathway

Alberti et al., 1999 Performed a case-control study on 83 autistic and 80 normal children