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Yes if they are not undergoing active treatment and if there is a clear indication such as post-surgical recovery, radiotherapy-related tissue repair, or immune support

Even though alternative models are available, such as animal models or ex vivo models, in vitro models offer higher experimental flexibility and reproducibility, making them a valuable tool for the understanding of pathophysiological mechanisms of several diseases, such as CVDs

Accumulation of cytosolic dsDNA contributes to fibroblast-like synoviocytes-mediated rheumatoid arthritis synovial inflammation

Note that Ser15-phospho-p53 foci are excluded from the nucleus after treatment with 25 mM FOXO4-DRI for 3 days