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Proteinprotein interaction (PPI) network analysis and qRT-PCR were used to validate the results, which confirmed that ferritin heavy 1 (FTH1), HIF-1, ferritin 1 (FT1), mitogen-activated protein kinase 8 (MAPK8), and lipid drop-coated protein 2 (PLIN2) were five FRGs, indicating that ferroptosis may be involved in the pathogenesis of PE, especially EOPE [30]

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We did not observe any changes in gene expression of TGF (Supplementary Fig