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Acknowledgments The authors would like to thank members of their laboratory for helpful and constructive advice

The Japanese company achieved nitrite concentrations of 0.1 micrograms per gram or less, which is equivalent to 0.1 parts per million (ppm)

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Exposure to ROS dissociated Nrf2 from Keap1 and allowed relocation of Nrf2 to the nucleus, where ARE responsive genes became actively transcribed

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