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Archived from the original on 23 July 2018

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This activation leads to decreased plasma autoantibody levels, reduced inflammatory cytokine expression, and an overall improvement in LN pathology [158]

This action is thought to subsequently elevate levels of insulin-like growth factor-1 (IGF-1), which is viewed as the primary agent responsible for the anabolic action of growth hormone

Sigma-1R enhances cellular Ca 2+ signaling capacity by stabilizing IP3R structure [59, 60], thereby enabling ovarian cells to rapidly adapt their metabolic state and maintain functional stability during cyclic hormonal fluctuations

Gastroenterology 127 , 17981808, doi: 10.1053/j.gastro.2004.09.049 (2004)