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It is available in multiple formulations, including oral suspensions, chewable, and even orally disintegrating tablets

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351 Nrf2 activation not only inhibits ROS, but also inhibits inflammation-related signaling molecules and the proliferation and migration of FLSs, thus alleviating RA synovitis effectively

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It is important to note that a highly electrophilic metabolite has a tendency to react with tissue nucleophilic groups such as -OH, -NH 2 and -SH and precipitate toxicities such as tissue necrosis, carcinogenesis, mutagenesis, teratogenesis, etc