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When taken orally, penta deca peptide arginate contacts the stomach lining, small intestinal epithelium, and colonic tissue sequentially during transit

Topical evidence is stronger and includes IRB-approved human trials

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This study revealed the function of p53 in renal fibrosis induced by different CaOx crystals and suggested that targeting the p53 deacetylation pathway may be a potential treatment for patients with nephrolithiasis