It has since been studied extensively as a model copper-carrier peptide, and is investigated for its role in skin and extracellular-matrix research, including work on collagen-related gene expression and fibroblast behaviour in cultured models
Frohlich, T
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Mechanistically, hyperactivation of Drp1 suppresses hexokinase 1 (HK1), a glycolytic enzyme localized to the mitochondria, inducing metabolic reprogramming that promotes NLRP3-driven inflammation and oligodendrocyte pyroptosis (Pradeepkiran and Reddy, 2020