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1,25-Dihydroxyvitamin D3 reduces TGF-3-induced fibrosis-related gene expression in human uterine leiomyoma cells

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Elevated Ca 2 concentrations within the mitochondria can trigger an increase in H 2 O 2 production, ultimately leading to mitochondrial dysfunction, excessive ROS generation, and initiation of apoptosis [448,454]

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doi: 10.1016/j.gendis.2016.04.007