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In hepatobiliary and pancreatic cancer cell lines (MIA PaCa-2), expression of HIF-1-targeted siRNA vectors reduced HIF-1 mRNA (~13% of control) and protein (~41% of control) levels, blocking tumor growth in vitro and in nude-mouse xenografts (214)

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Its deficiency is responsible for the dysfunction of the endothelial system

Additionally, in the field of molecular biology, a large number of studies are still needed to elucidate the specific mechanism of action of LC and explain its therapeutic effects on neurological and psychiatric diseases