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Sulfites are also present in many oral medications (adrenaline, isoprenaline, isoproterenol, isoetharine, phenylephrine, dexamethasone and injectable corticosteroids, dopamine, local anaesthetics, propofol, aminoglycoside antibiotics, metoclopramide and doxycycline) and topical creams and ointments (antifungals and corticosteroids)

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Neuropathy scores improved in seven patients, mostly in patients with immune-mediated neuropathy, but remained unchanged or worsened in the remaining five patients (two patients dropped out due to adverse events that were considered unrelated to B12)

Studies show safe doses up to 2,000mg for NR and 1,200mg for NMN