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Glutathione exists in redox equilibrium between disulfide (GSSG, oxidized form) and sulfhydryl (GSH, reduced form) forms and GSH levels in the living cells alter remarkably in response to the oxidative stress, which has been involved in many diseases and speeds up the aging process 5,6

Interactions of melphalan with glutathione and the role of glutathione S-transferase

Gussow, A

Glutathione biosynthesis occurs in two sequential, ATP-dependent enzymatic steps that take place in the cytosol: Step 1: The enzyme glutamate-cysteine ligase (GCL) combines glutamate and cysteine to form gamma-glutamylcysteine

Macpherson K, Cooper K, Harbour J, Mahal D, Miller C, Nairn M

Simultaneous high-speed recording of sonoluminescence and bubble dynamics in multibubble fields