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Treatments for cancer (radical prostatectomy or radiation) also carry much higher risks of severe incontinence and impotence compared to BPH treatments

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The androgen receptor (AR) signaling axis may influence the expression profile of LPA (unspecified species)-producing enzymes: androgen-sensitive LNCaP cells predominantly express AGK, whereas androgen-insensitive PC-3 and DU145 cells express ATX (46)

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