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Murthy CR, Rama Rao KV, Bai G, Norenberg MD (2001) Ammonia-induced production of free radicals in primary cultures of rat astrocytes

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However, standard therapies such as chemoradiation and surgical interventions frequently result in severe long-term morbidity, including dysarthria, dysphagia, dependence on tracheostomy or gastrostomy tubes, and disfiguring outcomes 4